Animals
- Jesse Eisenberg as Blu a macaw
- Anne Hathaway as Jewel a female macaw
- George Lopez as Rafael, a toucan
- Jemaine Clement as Nigel, a cockatoo
- Kristin Cheoweth as Gabi, a poison dart frog, Nigel’s Wife, and Asia’s Mom.
- Tracy Morgan as Luiz, a bulldog who is friends with Rafael,
- Will.i.am as Pedro a candrail
- Jamie Foxx as Nico a canary
- Bebel Gilberto as Eva, a toucan and Rafael’s Wife.
- Liam Neeson as Tanktaro a green macaw
- Bruno Mars as Roberto a spix's macaw
- Tine Tempah as Míoster a red macaw
- Neil Patrick Harris as Mauro a marmoset.
- Usher as Rizzle, a monkey.
- Willow Smith as Mazié, a red macaw and A Friend of Carla, Bia, and Tiago.
- Liam Neeson as Roman a red macaw
- Bruno Mars as Marlo a purple macaw
- Leslie Mann as Mango a pink-blue-purple flamingo
- Charlie Day as Benzok a red macaw
- Johnny Depp as Popnos
Humans
- Leslie Mann as Linda Gunderson
- Jake T. Austin as Fernando
- Rodrigo Santoro as Tulio Monteiro
- Hank Azaria as Mindos
- Willow Smith as Rosie
- Keke Plamer as Mary
- Abigal Berslin as Alice
- Quinn-Dempsty Stiller as Kyle
- Lyons Mathias as Trevor,
- John Turturro as Mantuors
- Jeffry Garcia as Tipa
- Gabiel Iglesias as Armando
Episodes (each season has 26 episodes)